Eteru.

One

Eteru.One Organogel

Psoriatic skincare

Our innovative Eteru.One formula combines the therapeutic benefits of Cannabigerol (CBG), curcumin, chrysin, cannabis terpenes, turmeric terpenes, and omega-3, -6, and -9 fatty acids to deliver exceptional results. This advanced topical preparation is meticulously crafted to address the multifaceted nature of psoriasis.

CBG and cannabis terpenes offer robust anti-inflammatory and antimicrobial properties, helping to reduce redness, swelling, and secondary infections. Curcumin, turmeric, and Cannabis terpenes provide powerful antioxidant and immune-modulating effects, neutralizing oxidative stress and balancing immune responses. Chrysin, a natural flavonoid, enhances anti-inflammatory activity and supports skin repair. Including omega-3, -6, and -9 fatty acids ensures optimal skin hydration and barrier function, preventing moisture loss and soothing dry, irritated skin. Together, these ingredients create a potent synergy, delivering comprehensive relief from the symptoms of psoriasis, promoting healthier skin, and improving the overall quality of life. This synergistic formulation offers a holistic approach to managing psoriasis, addressing multiple aspects of the condition to provide comprehensive relief and long-term skin health benefits.

Key Ingredients

  • Cannabis sativa Extract: An extract manufactured from Cannabis sativa cultivar with the highest concentration of terpenes and Cannabigerolic acid (CBGA), precursor of all cannabinoids with potent anti-inflammatory activity.

  • Omega-3-6-9 Fatty Acids Ethyl Monoesters: Pure and vegan, manufactured from 100% flaxseed oil.

  • Tetrhydrocurcumin: A colorless derivative of very well-known curcumin, turmeric’s principal active ingredient. It allows curcumin to provide its pleiotropic activities without the disadvantage of discoloring the skin.

  • Chrysin: A flavonoid, most abundant in passion fruit, propolis, and honeycomb.

Benefits

  • Reduces Inflammation:

    The combination of Cannabigerol (CBG), curcumin, chrysin, and cannabis terpenes provides potent anti-inflammatory effects. This helps to alleviate scaling, redness, swelling, and irritation commonly associated with psoriasis.

  • Soothes Itching and Discomfort:

    The product’s ingredients, particularly CBG and terpenes, have anti-itch properties that help to relieve pruritus, providing immediate comfort to affected areas.

  • Enhances Skin Barrier Function:

    Omega-3, -6, and -9 fatty acids and other nourishing components improve skin barrier integrity and hydration. This prevents moisture loss, reduces dryness, and enhances skin health.

  • Antioxidant Protection:

    Curcumin, chrysin, and turmeric terpenes offer potent antioxidant properties. They neutralize free radicals and reduce oxidative stress in the skin, helping to protect and repair skin cells.

  • Immune Modulation:

    Curcumin and cannabis terpenes help modulate the immune response, reducing the overactive immune reactions that contribute to the development and exacerbation of psoriasis.

  • Prevents Secondary Infections:

    The antimicrobial properties of cannabis, turmeric terpenes, and other ingredients help prevent and manage secondary infections in psoriatic lesions, promoting healthier skin.

  • Regulates Keratinocyte Proliferation:

    Eteru.One helps normalize the proliferation and differentiation of keratinocytes, addressing the hyperproliferation characteristic of psoriasis and promoting smoother, healthier skin.

  • Natural and Gentle:

    Formulated with natural ingredients, the product is gentle on the skin, making it suitable for daily use even on sensitive skin without the harsh side effects often associated with synthetic treatments.

  • Comprehensive Skin Nourishment:

    The blend of omega fatty acids and other bioactive compounds nourishes the skin deeply, promoting overall skin health and resilience.

  • Improves Quality of Life:

    By effectively managing symptoms and improving skin appearance and comfort, the product can significantly enhance the quality of life for individuals with psoriasis, boosting confidence and well-being.

Ideal Use Cases

  • Managing Psoriasis Flare-Ups:

    Use Eteru.One to alleviate the symptoms of psoriasis flare-ups, such as redness, swelling, and scaling. Its potent anti-inflammatory and soothing ingredients help reduce the intensity and duration of flare-ups.

  • Daily Maintenance:

    Incorporate Eteru.One into a daily skincare routine to maintain skin health and prevent the recurrence of psoriasis symptoms. Regular use can help hydrate the skin, restore lipid balance, reduce inflammation, and support a balanced immune response.

  • Post-treatment Care:

    Use after medical treatments or procedures for psoriasis, such as phototherapy or biologics, to enhance skin healing and provide additional relief from residual symptoms or irritation.

  • Dry and Irritated Skin Relief:

    Use Eteru.One is to soothe and hydrate dehydrated and irritated skin, even if it is not caused by psoriasis. The omega fatty acids and other nourishing components can significantly relieve and improve overall skin condition.

  • Stress-induced Psoriasis Management:

    Eteru.One can be used during stressful periods to mitigate flare-ups and maintain skin health for individuals whose psoriasis is triggered or worsened by stress.

  • Sensitive Skin:

    This product is ideal for individuals with sensitive skin who need a gentle, non-irritating product to manage their psoriasis symptoms without harsh chemicals or steroids.

Activities

  • Anti-inflammatory Effects:

    CBG, ω-3 fatty acids, curcumin, chrysin, and terpenes inhibit the production of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. These cytokines play a crucial role in the inflammatory processes associated with psoriasis. CBG has been found to reduce the activity of NF-κB, a protein complex that controls the transcription of DNA and plays a crucial role in inflammatory responses. Omega-3 fatty acids (like ALA and EPA) inhibit the production of pro-inflammatory eicosanoids, such as prostaglandins and leukotrienes, which are derived from arachidonic acid (an omega-6 fatty acid). Also, curcumin reduces the activity of cyclooxygenase-2 (COX-2) and lipoxygenase (LOX), enzymes involved in the inflammatory process.

  • Moisturizing and Barrier Repair:

    CBG helps maintain skin barrier function and hydration, crucial in preventing dryness and itching. Also, ω-3 fatty acids contribute to maintaining and improving the skin barrier, reducing transepidermal water loss and preventing skin dryness and irritation. Additionally, curcumin promotes collagen synthesis and wound healing, which can enhance the integrity of the skin barrier in psoriatic patients. A healthy skin barrier reduces transepidermal water loss and protects against irritants that can trigger itching.

  • Antioxidant Properties:

    All active ingredients exhibit antioxidant properties, which help reduce oxidative stress, a significant factor in the pathogenesis of psoriasis.

  • Promotion of Keratinocyte Differentiation:

    CBG and ω-3 fatty acids promote the differentiation of keratinocytes, which is beneficial in normalizing skin cell turnover in psoriatic lesions.

  • Inhibition of Keratinocyte Proliferation:

    Psoriasis is characterized by the hyperproliferation of keratinocytes. CBG and ω-3 fatty acids have shown potential in inhibiting these skin cells’ proliferation, thereby reducing psoriasis symptoms. In synergy with CBG, Curcumin inhibits the hyperproliferation of keratinocytes by modulating cell cycle regulatory proteins.

  • Immune Modulation:

    CBG and ω-3 fatty acids modulate immune responses, crucial in managing autoimmune conditions like psoriasis. They may help restore the balance between Th1 and Th2 cells, reducing autoimmune reactions.

  • Antimicrobial Activity:

    Psoriasis lesions are often susceptible to secondary infections. CBG has demonstrated antimicrobial properties, which can help prevent and manage infections in psoriatic skin.

  • Anti-Pruritic Effects:

    CBG, cannabis, and turmeric terpenes manage itching (pruritus) associated with psoriasis and other skin conditions through anti-inflammatory action, interaction with the cannabinoid system, and nerve desensitization.

  • Regulation of Lipid Mediators:

    ω-3 fatty acids (like EPA) can modulate the production of lipid mediators (like EPEA, PGE3, 12-HEPE) involved in inflammatory processes, supporting the reduction of psoriatic inflammation.

  • Cellular Functions:

    ω-3 fatty acids play a role in maintaining the structure and function of cell membranes, which is essential for overall skin health.

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